What puts me at risk of developing stretch marks?
Of the general population, these groupings have the highest risk of developing stretch marks: (2)
- Pregnant women: The frequency of stretch marks that occur as a result of pregnancy is estimated at between 43% and 88% (thus stretch marks are more common in women than men).
 - Adolescents: It is estimated that between 6% and 86% of teenagers experiencing growth spurts may develop stretch marks as a result. Of these, 35% to 40% of boys and up to 70% of girls may be affected. The average age for growth spurts among girls and boys is around 16 years. (3)
 - Those suffering from obesity: At least 43% of those suffering from obesity develop stretch mark formations.
 
Factors which may predispose a person to stretch marks
1. General population factors
- Genetics / a family history (decreased collagen and fibronectin genes are associated with the formation of stretch marks, but this is still largely unexplored in terms of research)
 - A personal history of stretch marks affecting the breast or thigh areas
 - Sudden weight gain / obesity or dramatic weight loss
 - Teenage growth spurts
 - Muscular gains through bodybuilding (exercise-induced muscle hypertrophy)
 
2. Medical conditions and medication use
- Cushing’s syndrome (which leads to the production of excess cortisol and weight gain)
 - Marfan syndrome (connective tissue abnormalities which influence growth and development)
 - Ehlers-Danlos syndrome (a condition characterised by stretchy skin prone to bruising)
 - Anorexia nervosa (an eating disorder whereby a person can experience dramatic weight loss, become dangerously underweight)
 - Chronic liver disease (the development of ascites / diluted superficial veins which result in an accumulation of fluid in the abdomen causing striae formations)
 - Systemic and topical corticosteroid medications (endogenous or exogenous) used in the treatment of eczema or psoriasis (chronic) – cortisone, hydrocortisone, prednisolone, triamcinolone and methylprednisolone.
 - Chemotherapy (the use of topical steroids to treat skin reactions and weight fluctuations as a side-effect of treatment may both lead to stretch marks)
 - Contraceptive pills (hormonal influences)
 - Neuroleptic treatment (antipsychotic medications have been linked to drug-induced endocrine changes in the body and weight gain – although this is still being researched)
 
3. Surgical procedures
- Breast augmentation and surgical procedures involving tissue expanders (often used in breast reconstruction procedures)
 - Organ transplantation procedures
 - Cardiac surgical procedures
 
4. Pregnancy
- A family history (inherent susceptibility) of developing stretch marks during pregnancy
 - Being pregnant during the teenage years or in one’s early 20s - (It is believed that younger skin may experience fragility in fibrillin (the glycoprotein involved in the formation of elastic fibres in connective tissues)
 - Excessive weight gain during pregnancy
 - Multiple gestation pregnancies
 - A woman’s pre-pregnancy BMI (body mass index) – A high pre-pregnancy BMI increases the risk of developing stretch marks
 - The presence of pre-pregnancy stretch marks affecting the breast/s
 - Carrying a baby with a higher birth weight or one that is determined as being large for their gestational age
 - Polyhydramnios (a condition wherein a pregnant woman has excess amniotic fluid in the amniotic sac)
 
References:
2. National Center for Biotechnology Information. 28 May 2017. Stretch Marks (Striae): https://www.ncbi.nlm.nih.gov/books/NBK436005/ [Accessed 26.02.2018]
3. Springer Link. 2006. Striae Distensae (StriaeAtrophicans, Striae Gravidarum, Stretch Marks): https://link.springer.com/chapter/10.1385/1-59259-906-0%3A223 [Accessed 26.02.2018]